BriefDefinitive Report CORRELATION OF STRUCTURE WITH T CELL RESPONSES OF THE THREE MEMBERS OF THE HLA-DRw52 ALLELIC SERIES
نویسندگان
چکیده
From the 'Department of Microbiology, University of Geneva Medical School, Geneva, Switzerland; lImmunogenetics Research, The Blood Center ofSoutheastern Wisconsin, Milwaukee, Wisconsin; the SInstitutefor Immunology and Hematology-Oncology Unit, La Tour Hospital, Geneva, Switzerland; IIPuget Sound Blood Center and Fred Hutchinson Cancer Research Center, Seattle, Washington; AAmerican Red Cmss Blood Service and Department of Medicine, University of Wisconsin, Madison, Wisconsin; and the "Department of Immunohematology and Blood Bank, University Hospital, Lieden, The Netherlands
منابع مشابه
Correlation of structure with T cell responses of the three members of the HLA-DRw52 allelic series
A third allele at the DRB3 locus, DRw52c, represents an intermediate sequence between DRw52a and DRw52b and may have arisen by a gene conversion-like event. The recognition of cells bearing these molecules by a number of alloreactive and antigen-specific DR-restricted T cell clones was analyzed. On the basis of a theoretical model of HLA class II structure, distinct amino acid clusters have bee...
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تاریخ انتشار 1989